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Compound 40 evicts TRF1 from the shelterin complex We developed a mass-photometry based assay to evaluate the ability of compound 40 to disrupt the TRF1 TRFH :TIN2 TBM interaction and subsequently evict TRF1 from the full shelterin complex

Glutathione is an endogenous antioxidant that supports liver detoxification and cellular defence against oxidative stress

If well tolerated with no concerns, consider either maintaining 0.1 mg once daily or increasing to 0.125 mg once daily based on response

Keep it refrigerated at all times

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