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M1 muscarinic receptors modify oxidative stress response to acetaminophen-induced acute liver injury

Goes EC, Dal Pont GC, Maiorka A, Bittencourt LC, Bortoluzzi C, Fascina VB, et al

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Twenty-four genes were identified that were differentially expressed in resistant or susceptible genotypes, including a tau class GST ( GSTU ) gene cluster (Wei et al., 2016

Activation of the HIF-1 pathway in SDH-deficient tumors is most likely the result of accumulating levels of succinate which is then transported into the cytosol via the action of the mitochondrial dicarboxylate transporter

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