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No causal relationship has been established in humans to date, and population-level data from large GLP-1 user cohorts have not shown a clear increase in MTC incidence.[5] That said, there are defined contraindications: GLP-1 therapy is not appropriate for patients with a personal or family history of MTC or Multiple Endocrine Neoplasia type 2 (MEN2 syndrome)

Tell your health care professional if you feel your heart racing or pounding in your chest and it lasts for several minutes Kidney problems (kidney failure)

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Key takeaways GLP-1 agonists are FDA-approved drugs for Type 2 diabetes or weight management

Obesity is one of the greatest threats to health because of the elevated risk of type 2 diabetes mellitus , hypertension, cardiovascular diseases and cancer