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2013, 304 (6): C508-518

That context informs a conversation with your provider it does not forecast results from a patch, pill, or injection

After announcing the state would initiate coverage of GLP-1s to combat obesity in September 2022 as part of their state employee health plan, the state reversed course and in January 2025 announced it was opting to end that coverage beginning July 1, 2025

The FDA warns that, unlike FDA-approved drugs (Mounjaro and Zepbound), you cannot be sure of the purity, quality, efficacy, or safety of compounded tirzepatide

For comparison, the SURMOUNT-1 trial for tirzepatide showed an average of 20.9% weight loss at the highest dose over 72 weeks

Reward mechanisms in obesity: new insights and future directions