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Degradation of glucosedependent insulinotropic polypeptide and truncated glucagonlike peptide 1 in vitro and in vivo by dipeptidyl peptidase IV

You can still find compounded versions, but they come with some risk

Studies have also shown that these drugs interact with other parts of the body, potentially reducing the risk of health conditions such as kidney disease, cardiovascular diseases, and heart attacks

These functions occur via binding and activation of their cognate secretin-like (class B) G protein-coupled receptors (GPCRs)

This has not been confirmed in humans, but as a precaution, neither drug should be used by people with a personal or family history of medullary thyroid cancer (MTC) or a rare genetic condition called MEN2