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The use of GLP-1 agonists may be considered in T1DM patients who are overweight or obese and not at glycemic goals

It slows digestion, reduces appetite, and supports metabolic health and studies show that it can result in significant weight loss

For Canada, the implications are similarly two-sided

TITR will likely be more clinically beneficial than TIR as fluctuations outside of TITR may be better predictors of complications and offer a better therapeutic window for intervention

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