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Growth and apoptosis Ex-4 significantly improves the survival of rat cortical neurons under oxygen/glucose deprivation (OGD) conditions through reduced apoptosis rates, increased expression of glucose-regulated protein 78, and decreased levels of C/EBP-homologous protein, indicating the role of Ex-4 in modulating unfolded protein response for protecting neurons from ischemic damage [56]
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Microbiome and nutraceutical GLP-1 modulation represents an emerging but still nascent category, with early patents [36] and scientific exploration [37] but minimal commercial traction to date
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Therefore, there is an urgent need to identify effective approaches for heart regeneration
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