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Prx1 Cys83 binds to cullin-3, a ubiquitin ligase modulating Nrf2 ubiquitination [150] , and thereby inhibits degradation of Nrf2 allowing transcription of anti-ferroptotic enzymes [149]

Diet and exercise Participants were encouraged to maintain their normal dietary intake during an initial baseline week

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According to some research, those who consume more flavonoids in their diets than those who consume the least have a 47% increased risk of cardiovascular disease (579)

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