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In this study, researchers evaluated the effects of Retatrutide on 338 adults with obesity , all without diabetes, over the course of 48 weeks

Zepbound is generally more effective, with studies showing up to 21% weight loss, compared to ~15-19% for high-dose semaglutide

JAMA 2024;331:3848.PubMedPMC 95

Provitalize and Pendulum both fall into this newer category

Studies show that stopping the medication can sometimes, but not always, cause a persons weight to creep back up, along with blood pressure, blood sugar and cholesterol levels

If nausea persists beyond the first 46 weeks, discuss prescription anti-nausea options with your PlexusDx clinician