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Bioactivities of berberine metabolites after transformation through CYP450 isoenzymes

She serves on the scientific advisory board of Novo Nordisk, which makes both medications

The age of the different groups was: obese control [6 females (F)/2 males (M)] median age 42 years [3551, 95% CI], VSG group [4 F/2 M] median age 43.6 years [3552, 95% CI], RYGB group [5 F/1 M] median age 45 years [3056, 95% CI], and there was no significant difference between groups

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In normal humans, the rate of synth is est to be ca 1.2 umol/kg/day