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Federal law generally bars compounders from making copies of FDA-approved drugs, but sections 503A and 503B of the Federal Food, Drug, and Cosmetic Act allow compounding under certain circumstances, including during shortages

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However, a significant decrease in cell viability was observed when these compounds were used at 10,000 M, indicating their cytotoxic effect

Cholesterol accumulation decreases the concentration of OSCs, ultimately accelerating the progression and metastasis of CRC (Jun et al., 2021)