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We further demonstrate that in female mice, sensitivity to the aversive properties of these drugs is estrous cycle-dependent, with responsiveness being amplified during proestrus, when circulating estrogen levels peak, and minimized during diestrus, when estrogen levels are low

Int J Sports Med 1989;10(3):169-174

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Research models indicate that BPC-157 may interact with intracellular signaling systems relevant to vascular growth via angiogenic signaling and inflammatory regulation via attenuation of pro-inflammatory pathways