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This is because digestive enzymes, which are more active during meals, readily break down glutathione
J Biol Chem (1997) 272(28):17694702.10.1074/jbc.272.28.17694 140 StofegaMRHerringtonJBillestrupNCarter-SuC
ONOO- can induce damage to cellular structures, including lipids, proteins, and DNA, leading to oxidative stress and further exacerbating inflammation and tissue injury (149)
The most accurate framing is that the gut-skin connection is real, the research base is growing, and the best products are the ones that respect that complexity rather than oversimplify it
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