2024;28:e70090
Hydration is also key as GLP-1 medications can reduce thirst
Either people really have to accept this as a treatment for life,, or we in science need to think really, really hard, how to support people when they stop the drug. While the study did not show causality, Jebb speculated that the difference in how fast people put weight back on could be due to the fact that diets are hard and people have to practise restraint to lose weight, whereas if you are taking a drug that knocks your hunger out completely, you dont have to make that effort
Methionine specifically activates S-adenosylmethionine (SAMe), the universal methyl donor for hundreds of enzymatic reactions including those that regulate fat metabolism and neurotransmitter synthesis
whether either of these translates to meaningful changes in fibromyalgia pain mechanisms is currently a hypothesis rather than an established finding
Because of this, if an athlete is prescribed a GLP-1, it's important to be aware of the potential for Relative Energy Deficiency in Sport (REDs) due to under-fueling