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Finally, long-term safety follow-up (12 months) is essential to assess risks of chronic Nrf2 activation (e.g., cancer progression) or antioxidant interference with physiological ROS signaling, highlighted by the bardoxolone methyl experience in diabetic kidney disease (Nangaku et al., 2020)

The authors thank Stine-Mathilde Dalskov for their assistance in the interpretation of efficacy and safety data

BPC-157's presence on the WADA Prohibited List makes it inappropriate for tested athletes regardless of its dietary supplement status in the broader consumer market

A licensed provider can help match the dose and form to your medical history

The companys founders pled guilty to federal charges in December 2025

However, other studies found no significant cognitive benefits of vitamin E supplementation