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Therefore, this article is timely in reviewing the characteristics and main molecular mechanisms common to renal, hepatic, and cardiac toxicity previously described, in addition to addressing the main validated strategies for the current management of these adverse events in clinical practice

It is very important to inform your doctor about the medications and supplements you are taking to ensure safety

and Mandal, P.K

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In addition, several p53 mutations induce the expression of oncogenic proteins, resulting in a dominant-negative (DN) effect on wild-type p53