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IGF-DES has been characterised in peer-reviewed research since the late 1980s, with studies spanning receptor binding, cell biology, tissue repair, and IGFBP interaction

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10.1056/NEJMoa1603827 [DOI] [PMC free article] [PubMed] [Google Scholar] 27

The SURMOUNT data also showed impressive metabolic improvements

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As liver iron overload is a hallmark of ALD, it would be interesting to investigate whether some iron homeostasis-related molecules could serve as biomarkers predicting ALD risks in alcoholics