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C.Pentcheva-HoangT.CarstensJ

Helps improve the appearance of uneven skin tone and stubborn pigmentation over time

The first Phase 3 trial to report results, TRIUMPH-4, was published on 11 December 2025

180 WilsonJMNikooienejadARobinsDARoellWCRiesmeyerJSHauptAet al

When that signal drops, bowel activity can rebound sharply, and the result is cramping, loose stools, nausea, and vomiting that can make eating or drinking feel like work

Variations in dosage and administration routes could influence the types and severity of skin findings, underscoring the need for additional research, they said