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From month 6 onward at maintenance dose, the rate slows but doesn't stop

doi: 10.1080/00325481.2021.2006514 48 TsaiMCLiouCWLinTKLinIMHuangTL

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90 In this process, epithelial cells lose their characteristic structure and functions, including cell polarity, tight junctions, and intercellular adhesion, and gain the morphology and functions of mesenchymal cells, including cell migration, invasion, and resistance to apoptosis

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