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GLP-1 receptor agonists and SGLT-2 inhibitors in patients with versus without cardiovascular disease: A systematic review, meta-analysis, and trial sequential analysis
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This synergistic interaction explains why PEM patients responses to exercise-induced stress far exceed normal thresholds and why mitochondrial dysfunction may be a consequence of sustained immune-metabolic reprogramming rather than an isolated, spontaneous event (119, 120)
Metabolism of taurine in humans In animal cells, taurine undergoes limited catabolism by taurine:pyruvate transaminase or taurine:-ketoglutarate transaminase, which catalyzes the transamination of taurine with pyruvate or -ketoglutarate to form 2-sulfoacetaldehyde (also known as 2-oxoethanesulfonate, 2-hydroxyethanesulfonate, or isethionate) and l-alanine or l-glutamate (Read and Welty 1962)
