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Additionally, GLP-1RA is associated with gastrointestinal adverse events, which may cause absorption of minerals and nutrients and thereby interfere with the beneficial function of GLP-1RA on bone physiology ( It is possible that different GLP-1 agents have divergent effects on bone fractures, as shown in another meta-analysis of RCTs that ended in December 2013
doi: 10.1016/j.xcrm.2025.101928 50 RashmiRJayachandranKZhangJMenonVMuhammadNZahnerMet al
Theres also the issue most people are never told about: A significant part of the weight lost can be lean mass
Useful for catching imbalances that can worsen with vomiting or diarrhea early in treatment
Well, it's up about 40 percent in the last year