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Although unproven, nonglycemic hemodynamic effects may promote cardiovascular benefits with SGLT2i (Figure 1)
Either way, the decision to take a GLP-1 should always be made individually, with guidance from a qualified healthcare team who understands a person's full health history, goals, and training demands
2 For example, a related study found that rats given GLP-1 RA showed a decreased desire for alcohol, while another drug, Exendin-4, seemed to reduce drug-seeking behaviors related to heroin
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Globally, demand for these drugs has surged, particularly in the United States and Europe, where they have become a major part of conversations around obesity treatment