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The hypothesized scheme was developed on the basis of the assumption that the 718C variant of the GPX4 gene is responsible for an increased activity or level of this enzyme in the brain

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In insulin-treated patients, disordered gastric emptying, even when not associated with gastrointestinal symptoms, can cause a mismatch between the onset of insulin action and the availability of absorbed carbohydrate, leading to suboptimal glycaemic control

Further evaluation may be warranted in children with red flags that might suggest an organic etiology (Table 3)

Regular check-ins with your healthcare provider can help you stay on track with your goals