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Summary: Vitamin B12 toxicity from supplementation is extremely rare, but persistently elevated serum levels may indicate underlying liver disease, kidney dysfunction, or haematological disorders requiring medical investigation

Archived from the original on July 23, 2011

doi: 10.1371/journal.pone.0025792

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Thyroid issuesmost commonly hypothyroidism, hyperthyroidism, and, less frequently, thyroid stormare the most commonly reported endocrine toxicity following ICI medication in clinical trials (Barroso-Sousa et al