In vivo, PNPLA2 is expressed in breast cancer cells and not in normal breast epithelial cells, and PNPLA2 expression is correlated with poor prognosis (211)
Neurologic aspects of cobalamin (B12) deficiency
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Cell Chem Biol (2021) 28(6):76575.e5
However, such studies do acknowledge that conflicting results exist, with one study specifically suggesting that increased B12 intake may lead to a quicker falling off of melatonin and a shorter sleep duration