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J Ren Nutr

Acknowledgments We thank Alex Pontefract (Space Exploration Sector, Johns Hopkins University Applied Physics Laboratory, Laurel, MD, USA) and Mario Toubes-Rodrigo (AstrobiologyOU, The Open University, UK) for the sediment samples from Basque Lake no2

Cells treated with test compounds were washed with PBS and incubated with 10 M 2,7-dichlorofluorescein diacetate (DCFH-DA) at 37 C for 30 min, followed by washing with PBS, digestion with trypsin, and collection

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The study identified a total of 100 independent and significantly associated risk single nucleotide variants (SNVs), with 60 of these SNVs correlating to more than one OA phenotype