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As more patients began seeing unintentional weight loss during treatment, researchers started taking a closer look

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In addition, the enteric nervous system (ENS), which is a recognized second brain that can regulate many GI functions independent of CNS action, can also act as an intermediate in relaying gut-derived information to the CNS 25

The nutrition approach should be individualised based on personal preferences, socioeconomic status, cultural backgrounds and comorbidities