Some studies suggest that GHK-Cu fragments or metabolites might still have biological activity even if the intact peptide is not fully absorbed
This imbalance contributes to airway inflammation, airway hyperreactivity, and epithelial injury, which are hallmarks of airway disorders
show efficacy by alleviating histopathological damage and counteracting oxidative stress (Wang et al., 2023)
For a comprehensive overview, see: GHK-Cu: The Anti-Aging Copper Peptide with Over 100 Published Studies
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This upregulation exhausts intracellular GSH, leading to ROS buildup and oxidative DNA damage that can ultimately generate TP53 mutations, a process that is halted when CHAC1 is knocked down (Wada et al., 2018)