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In a neonatal piglet-based ARDS model, it was found that experimental supplementation with phosphatidylglycerol reduced interleukin-6 (IL-6) and alveolar apoptosis while preserving the alveolar-capillary barrier, thereby reducing pulmonary edema

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Moreover, dietary supplementation with TMAO significantly decreased the expression of both enteral cholesterol transporters Niemann-Pick C1-like1 (Npc1L1), which transports cholesterol into enterocytes from the intestinal lumen, and ABCG5/8, which transports cholesterol out of enterocytes into the gut lumen (Koeth et al., 2013)

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