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14,15 Potential Direct Effects on the Heart Although the systemic indirect effects of GLP-1RAs are well established as the primary drivers of their clinical benefit in HF, emerging preclinical and mechanistic evidence suggests GLP-1RAs may also exert some direct cardioprotective effects, as discussed below
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- Graf Neuroscience & Biobehavoral Reviews How DSIP Works (Mechanism of Action) DSIPs exact mechanisms are still being studied, but evidence suggests it influences several key systems in the body that regulate sleep, stress, and hormone balance
Greater gains were also obtained in aerobic capacity and efficiency after HIT, with additional improvements in cognitive functions, suggesting that the amount and intensity of stepping practice may be important in improving locomotor outcomes in patients with chronic TBI [145]
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