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(8) conducted a comparative study in obese diabetic (db/db) mice treated with either semaglutide or tirzepatide

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Tirzepatide, a dual-agonist peptide, has shown significant results with a 22.5% weight loss over 72 weeks at a 15 mg dose (Jastreboff et al., NEJM), making it one of the most effective therapies for obesity

1 Introduction Intermittent fasting (IF) has gained attention as an effective strategy for reducing body weight and improving metabolic health