High pressure within blood vessels over time causes damage to arterial linings
Medium-chain triglycerides (MCTs) consisting of decanoate (C10:0) can improve glucose tolerance and inhibit HFD-induced obesity in mice by stimulating GLP-1 secretion through GPR84 [148]
Glitza IC, Rohlfs M, Guha-Thakurta N, Bassett RL, Bernatchez C, Diab A, Woodman SE, Yee C, Amaria RN, Patel SP, Tawbi H, Wong M, Hwu WJ, Hwu P, Heimberger A, McCutcheon IE, Papadopoulos N, Davies MA
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Although research on the treatment of ALD with these agents targeting gut microbiota has gradually deepened from efficacy observation to mechanism exploration, there are still many deficiencies in the breadth and depth of the current research, such as narrow research scope, unclear target and the lack of clinical trials