We will explore its physiological functions, the development of powerful therapeutic drugs that harness its effects, and the wide-ranging benefits that extend far beyond the bathroom scales
In the Phase 2 retatrutide trial published in the New England Journal of Medicine (2023), participants at the highest dose (12 mg) achieved a mean body weight reduction of approximately 24.2% over 48 weeks
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It does this by stimulating the release of insulin and reducing the release of glucagon, a hormone that raises blood sugar
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These incretin mimetic GLP-1 and GIP/GLP-1 drugs that help you lose body weight by slowing down digestion and increasing the transit time of food in the stomach have gained widespread popularity in the past half a decade