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e., RAP1-GTP levels) is associated with melanoma cell proliferation, we performed multiplexed quantitative IHC of a commercially available melanoma TMA (consisting of 32 Stage II and III primary lesions and 16 lymph node metastases) for RAP1-GTP protein and the proliferation marker Ki67 (Fig
doi:10.1034/j.1601-183x.2003.00037.x 107. Russo, A
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As will be highlighted in the following, this can play a role in the proposed explanation of the important biological role of metallated MTs in several organs where the accumulation of metals over lifetime ultimately generates its functional failure or the onset of cancer
