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19 Following further translocation to the mitochondria, activated phosphorylated JNK initiates a cascade in which JNK binds to the outer mitochondrial membrane scaffold protein Sab, inhibiting electron transport and thereby increasing the generation of ROS and peroxynitrite

D.WangS.AnuarF.QianY.BjrkholmB.SamuelssonA.et al

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(2009) showed that s permatocyte-specific Gpx4 -/- knockout mice are completely infertile , whereas GPx4 +/ and transgenic rescued Gpx4 -/- knockout mice were fully fertile

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Diet-induced obesity in two C57BL/6 substrains with intact or mutant nicotinamide nucleotide transhydrogenase (Nnt) gene