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The pattern most often described now has two phases: Loading / tolerance phase: roughly 50 mcg 1 unit on a U-100 insulin syringe at the standard 10 mg / 2 mL reconstitution subcutaneously once daily for about 7 days in a row, or until noticeable color begins to appear

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In addition, these patients are at increased risk of diabetes, hypertension, and hyperlipidemia

Li et al., 2020)

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