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doi: 10.1152/ajpendo.00330.2023 170 NauckMAMeierJJ

427,428 Interestingly, no significant adverse events were documented compared to the placebo group

In the absence of oxygen, ATP production from mitochondrial oxidative phosphorylation declines in relation to the degree of ischemia, and the heart switches to alternative energy substrates for anaerobic ATP production 26

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