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GLP-1R Antagonist 1 Based on 7 publication(s) in Google Scholar GLP-1R Antagonist 1 (compound 5d) is an orally active, CNS penetrant and non-competitive antagonist of glucagon-like peptide 1 receptor (GLP-1R) , with an IC 50 of 650 nM

ClinicalTrials.gov TRANSCEND-T2D-1: A Study of Retatrutide (LY3437943) in Adult Participants With Type 2 Diabetes (NCT06354660)

Reviewed July 15, 2024

This multi receptor approach is intended to increase satiety, reduce appetite, improve blood sugar control, and stimulate energy expenditure

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