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Available data suggests timelines of 3 to 6 weeks for noticeable improvement with KPV

McEleny K, et al

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Diabetic peripheral neuropathy: evidence for apoptosis and associated mitochondrial dysfunction

After incubation, the suspension was centrifuged at 2000 rpm for 5 min, and the supernatant was measured at 540 nm using a microplate reader

In addition, be especially cautious of preservatives like sodium benzoate, sorbic acid, BHA, and BHT