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The EMPEROR-Reduced trial demonstrated the efficacy of empagliflozin versus placebo in 3,730 patients with HFrEF (mean LVEF 27%), hospitalised for HF within the previous 12 months and with higher levels of natriuretic peptides compared with DAPA-HF

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Store vials in carton until their use to protect from light

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Multiple long-acting GLP-1RAs reduce rates of major adverse cardiovascular events (MACE) in outcome trials of people with type 2 diabetes [102], heightening interest in understanding the mechanisms linking GLP-1R activation to cardioprotection