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In vitro, synovial fibroblasts exposed to GSH reduced IL-6 secretion, suggesting a retreat of synovial inflammation [6]

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Research indicates it may also have effects on appetite regulation and metabolic processes through its interaction with other melanocortin receptor subtypes

with monthly dosing, there was continued weight loss and at 60 weeks at the highest dose (4.8 mg monthly) there was 15% weight loss from baseline, Buse said during the presentation