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Patients with diabetes mellitus (DM), acute pancreatitis, bariatric surgery, or severe renal failure were excluded

By improving insulin sensitivity and overall metabolic status, GLP1 receptor agonists can normalize reproductive hormone signaling in insulinresistant women (such as those with PCOS), which may help restore more regular ovulation

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Data from STEER [33] suggests lower incidence of 3-point MACE with semaglutide compared to tirzepatide in patients with overweight/obesity and ASCVD without diabetes