Research has shown that capsaicin activated by transient receptor potential vanilloid 1 (TRPV1) can induce calcium influx and octamer-binding transcription factor 4A (OCT4A) degradation, leading to autophagy and losing of stemness in ATC cells [288, 289]
No effect was seen by Koehler et al (58) and in the work of Tatarkiewciz et al (108) high doses of exenatide inhibited the pancreatitis
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