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Clinical trial data and real-world evidence give a clear picture: Incidence: The MHRA Summary of Product Characteristics for tirzepatide lists GORD as a common adverse reaction (occurring in 1 in 10 to 1 in 100 patients)

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Dosage should be determined through individual clinical assessment not extrapolated from a single study or a supplement label

Polycystic ovary syndrome (PCOS), thyroid disorders (both hypothyroidism and hyperthyroidism), and hyperprolactinaemia can all disrupt normal menstrual patterns

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