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Therapeutically, miRNAs use is challenged by some issues

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These effects are achieved through different mechanisms: 1) impairing of the ATP-gated P2X7 receptor (one on the main danger signal sensors on cells), that activates the NLPR3 inflammasome

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The sirtuin family member SIRT-1 is a protein lysine deacetylase that regulates several physiological processes, including energy production, inflammatory responses, cell survival, DNA repair, tissue regeneration, and stress responses