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The current evidence suggests that tirzepatide, like other GLP-1 medications, works best as a long-term or indefinite treatment

Vegetarians are another group that often supplement their diet with vitamin B12 per day

Anyone who tells you otherwise is not being straight with you

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Outside of clinical trials, pre-licence access in the UK may theoretically occur via the MHRA's Early Access to Medicines Scheme (EAMS), though no such scheme for retatrutide is publicly available at the time of writing