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Most are gastrointestinal, dose-dependent, more common early in titration, and tend to ease with continued treatment

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Gentle swirling or rolling the vial between palms suffices

Statements Author contributions FL: Software, Supervision, Methodology, Data curation, Conceptualization, Validation, Investigation, Formal Analysis, Funding acquisition, Resources, Writing review and editing, Visualization, Project administration, Writing original draft

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To this end, GLP-1 is not produced in response to intravenous glucose and instead, the amount of GLP-1 released is relative to the size of a meal and is correlated to the rate of gastric emptying [29]