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The medical condition resulting from inadequate production and/or utilization of hGH is called growth hormone deficiency (GHD)

Combination regimens incorporating PD-1/PD-L1 inhibitors with modalities such as chemotherapy, radiotherapy, complementary immunotherapies or targeted agents have demonstrated enhanced therapeutic efficacy (181)

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Then all animals were randomly divided into five groups (n=10) as follows: group I (model control) rats were administrated plain hydrogel alone