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Consensus sequence One approach that has been taken is to design vaccine antigens that are enriched for conserved T and B-cell epitopes either as a consensus sequence (which is the closest natural circulating sequence to a bioinformatically calculated consensus) or as a string of epitopes taken out of their natural context within the viral protein (Fig

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Act as a positive prognostic indicator for a good subsequent response to a carpal tunnel decompression

However, such a large conformational change is not likely to be caused directly by agonist-binding since there is little interaction between TM7 and both agonists

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