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This study design differs from the single-dose lean-rat experiment in species, dosing schedule, duration, and endpoint, and the ED 50 values from the two studies should not be treated as directly comparable or rank-ordered across studies

Modulatory profiling identifies mechanisms of small moleculeinduced cell death

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Quinpirole (Q111) and PTX (SAE0066) were purchased from Sigma-Aldrich

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doi: 10.1038/ki.2009.157